The Women's 1s are already through their Scottish Cup tie following a 1-0 win at home to GHK on Monday night. However, Saturday sees several other teams in knockout action.
The Men's 1s host Erskine Stewart's Melville in the Scottish Plate (1330). Western are favourites to win this one and progress in the consolation competition.
Also involved in plate action are the 3s who welcome Dundee Wanderers 4s in the Reserve competition (1200) and the Women's 2s who play Grange 3s (1500). The Men's 2s have a bye and therefore do not play this weekend.
The Men's 4s and 5s have home league fixtures which bookend the day. The 4s - still chasing a first win - face Dumfries at 1030 and the 5s round off the Auchenhowie action against Ayr 2s at 1630.
The Women's 3s play on Sunday at home to Strathclyde University (1230). The 1s have a big league game in Dundee against Grove Menzieshill while the 2s are away to Troon.